Potensi Senyawa Aktif Minyak Atsiri Kulit Kayu Manis sebagai Agen Pengusir Tikus (Rodent Repellent): Literature Review
DOI:
https://doi.org/10.62951/habitat.v4i2.365Keywords:
Cinnamaldehyde, Cinnamomum Burmannii, Essential Oil, Herbal Pest Control, Rodent RepellentAbstract
Cinnamon (Cinnamomum spp.) bark essential oil contains bioactive compounds—primarily trans-cinnamaldehyde and eugenol that show broad-spectrum biological activity. Rodents (Order Rodentia) pose persistent threats to human food security, public health, and household safety. Conventional rodent control relies heavily on synthetic rodenticides, which carry risks of non-target toxicity, environmental persistence, and human poisoning. Herbal repellents, by contrast, deter rodents through olfactory and gustatory cues without killing them, making them a safer and more ecologically sound alternative. This literature review aims to evaluate the scientific evidence on the potential of essential oil from cinnamon bark as a rodent repellent (rodent repellent) agent. A systematic search of primary peer-reviewed journals published between 2019 and 2026 was conducted. The reviewed evidence indicates that trans-cinnamaldehyde, the dominant constituent of cinnamon bark essential oil, elicits strong repellent responses in a range of arthropod and rodent pest species through mechanisms including olfactory receptor activation, acetylcholinesterase disruption, and ionotropic receptor binding. Formulation strategies such as nanoemulsions, chitosan nanoparticles, and gel matrices significantly enhance repellent efficacy and durability. The findings support the conclusion that cinnamon bark essential oil is a scientifically promising, biodegradable, and low-toxicity candidate for herbal rodent repellent development, warranting further in vivo bioassay and field evaluation specifically targeting rodent species.
References
Beniaich, G., Zouirech, O., Allali, A., Bouslamti, M., Maliki, I., El Moussaoui, A., Chebaibi, M., Nafidi, H.-A., Bin Jardan, Y. A., Bourhia, M., & Taleb, M. (2023). Chemical characterization, antioxidant, insecticidal and anti-cholinesterase activity of essential oils extracted from Cinnamomum verum L. Separations, 10(6), 348. https://doi.org/10.3390/separations10060348
Cao, J., Kuang, C., Zhou, Y., Zhang, H., Wang, Y., & Zhou, J. (2024). Parthenogenetic Haemaphysalis longicornis acetylcholinesterases are triggered by the repellent effect of cinnamaldehyde, a primary compound found in cinnamon oil. Ticks and Tick-Borne Diseases. https://doi.org/10.1016/j.ttbdis.2024.XXXXXX
Hary, W., Putriningtyas, N. D., Nugroho, E., Maulidah, H., Sari, E. Y. U., Putri, E. Y., & Rahmawati, A. (2021). Potensi ekstrak kayu manis sebagai insektisida Aedes aegypti. Book Chapter Kesehatan Masyarakat, 5.
Johan, N. A. A., Hasmadi, H. H., Peter, K. S., Nasir, S. H., El Bakri, H. M., & Misni, N. (2025). Development of multifunctional textiles with mosquito repellent and antibacterial properties using microencapsulated lemongrass essential oil on cotton–polyester fabric. Fibers and Polymers, 26, 5455–5464. https://doi.org/10.1007/s12221-025-01178-7
Khandehroo, F., Moravvej, G., Farhadian, N., & Ahmadzadeh, H. (2023). Enhanced repellent and anti-nutritional activities of polymeric nanoparticles containing essential oils against red flour beetle, Tribolium castaneum. Scientific Reports. https://doi.org/10.1038/s41598-023-XXXXX
Kuang, C., Shi, H., Cao, J., Zhou, Y., Zhang, H., Wang, Y., & Zhou, J. (2025). HL-IR mediates cinnamaldehyde repellency behavior in parthenogenetic Haemaphysalis longicornis. PLoS Neglected Tropical Diseases, 19(3), e0012877. https://doi.org/10.1371/journal.pntd.0012877
Kurniawan, D. W., Agustina, V. N., Sunarto, Wibowo, G. A., & Hidayat, M. Z. S. (2022). Formulation of cinnamon bark essential oil gel as mosquito repellent. International Journal of Applied Pharmaceutics, 14(1). https://doi.org/10.22159/ijap.2022v14i1.43034
Mahran, H. A., Aboelhadid, S. M., & Hassan, K. M. (2023). Synthesis and efficacy of cinnamon oil formulations and their sustainable release against common house mosquito larvae. Beni-Suef University Journal of Basic and Applied Sciences, 12, 118. https://doi.org/10.1186/s43088-023-00455-9
Mahmoud, H. A., Azab, M. M., & Sleem, F. M. A. (2023). Bioactivity of Cinnamomum verum powder and extract against Cryptolestes ferrugineus S., Rhyzopertha dominica F., and Sitophilus granarius L. (Coleoptera). International Journal of Tropical Insect Science, 43, 629–636. https://doi.org/10.1007/s42690-023-00974-z
Maslahah, N., & Nurhayati, H. (2020). Kandungan senyawa bioaktif dan kegunaan tanaman kayu manis (Cinnamomum burmannii). Buletin Tanaman Rempah dan Obat.
Medikawanti, Y. A., Windarso, S. E., & Rubaya, A. K. (2026). Pengaruh spray minyak atsiri kulit kayu manis (Cinnamomum burmannii) terhadap daya tolak nyamuk Aedes aegypti. Keslingmas, 45(1). https://doi.org/10.31983/keslingmas.v45i1.14146
Moungthipmalai, T., Puwanard, C., Aungtikun, J., Sittichok, S., & Soonwera, M. (2023). Ovicidal toxicity of plant essential oils and their major constituents against two mosquito vectors and their non-target aquatic predators. Scientific Reports. https://doi.org/10.1038/s41598-023-XXXXX
Narayanankutty, A., Kunnath, K., Alfarhan, A., Rajagopal, R., & Ramesh, V. (2021). Chemical composition of Cinnamomum verum leaf and flower essential oils and analysis of their antibacterial, insecticidal, and larvicidal properties. Molecules, 26(20), 6303. https://doi.org/10.3390/molecules26206303
Prasetyorini, D., Moerfiah, & Ambarwati, D. (2019). Lilin aromatik minyak atsiri kulit batang kayu manis (Cinnamomum burmannii) sebagai repelen lalat rumah (Musca domestica). Ekologia: Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup, 19(2), 55–64.
Quasim, M. A., Karn, A. K., Paul, S., Hmar, E. B. L., & Sharma, H. K. (2023). Herbal rodent repellent: A dependable and dynamic approach in defiance of synthetic repellent. Bulletin of the National Research Centre, 47, 82. https://doi.org/10.1186/s42269-023-01055-4
Soonwera, M., Moungthipmalai, T., Takawirapat, W., & Sittichok, S. (2023). Ovicidal and repellent activities of several plant essential oils against Periplaneta americana L. and enhanced activities from their combined formulation. Scientific Reports. https://doi.org/10.1038/s41598-023-XXXXX
Stuart, A. M., Jacob, J., Awoniyi, A. M., Costa, F., Bosma, L., Meheretu, Y., Htwe, N. M., Williamson, S., Eddleston, M., Dalecky, A., & Willis, S. (2025). Alternative domestic rodent pest management approaches to address the hazardous use of metal phosphides in low- and middle-income countries. Journal of Pest Science, 98, 89–111. https://doi.org/10.1007/s10340-024-01825-7
Syarli, S., Elisma, Lestari, U., Rahmadona, T., Herawati, A., Najwa, S., & Delfina, R. A. (2025). Formulasi dan uji efektivitas repellent spray gel minyak atsiri daun kayu manis (Cinnamomum burmannii) sebagai penolak nyamuk. Journal of Pharmaceutical Care and Sciences, 6(1), 40–50. https://doi.org/10.33859/jpcs.v6i1.772
Yuniarti, N., Anwar, D. I., & Khumaisah, L. L. (2023). Formulasi eau de parfum berbahan dasar minyak atsiri khas Sukabumi sebagai repellent terhadap Aedes aegypti. JC-T (Journal Cis-Trans): Jurnal Kimia dan Terapannya, 7(2). https://doi.org/10.17977/um0260v7i22023p007
Zhou, Y., Cao, J., Wang, Y., Battsetseg, B., Battur, B., Zhang, H., & Zhou, J. (2023). Repellent effects of Chinese cinnamon oil on nymphal ticks of Haemaphysalis longicornis, Rhipicephalus haemaphysaloides, and Hyalomma asiaticum. Experimental and Applied Acarology, 91, 497–507. https://doi.org/10.1007/s10493-023-00855-7
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Habitat: Jurnal ilmiah ilmu Hewani dan Peternakan

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.



